Reverse Transcriptase | Function, Structure & Application
Learn the reverse transcriptase enzyme definition. Explore the functions and structure of reverse transcriptase, and discover which organisms have this enzyme.
The Biotechnology Revolution: PCR and the Use of Reverse …
Jun 27, 1970 · At this point, the reverse transcriptase enzyme is added, and this enzyme proceeds to utilize the mRNA strand as a template for the synthesis of a complementary DNA …
The regulations of telomerase reverse transcriptase (TERT) in cancer
Jan 26, 2024 · Telomerase reverse transcriptase (TERT) is a key component of telomerase. Human TERT was first cloned in 1997 [5, 8, 9, 10], eight years after telomerase was first …
Discovery and evolution of RNA and XNA reverse transcriptase …
Jul 20, 2020 · The ability of reverse transcriptases (RTs) to synthesize a complementary DNA from natural RNA and a range of unnatural xeno nucleic acid (XNA) template chemistries, …
The reverse transcriptase domain of prime editors contributes to …
Feb 17, 2025 · Reverse transcriptase (RT) has been shown to play a role in double-strand break repair in bacteria, yet the impact of the RT component of prime editors (PEs) on normal …
Reverse transcription-quantitative PCR (RT-qPCR) without the …
Jul 15, 2023 · For all samples, negative controls without reverse transcriptase enzyme were also prepared. Quantitative real-time PCR (qPCR) for satellite DNA expression analysis
Regulation of human telomerase in homeostasis and disease
Apr 2, 2020 · Telomere length is maintained by telomerase, which comprises a reverse transcriptase and a template RNA. Telomerase activity is disrupted in several genetic …
Protein-primed homopolymer synthesis by an antiviral reverse …
May 28, 2025 · A bacterial reverse transcriptase synthesizes polydeoxyadenylate to provide population-level immunity against viral infection.
Structural basis for pegRNA-guided reverse transcription by a
May 29, 2024 · The prime editor system composed of Streptococcus pyogenes Cas9 nickase (nSpCas9) and engineered Moloney murine leukaemia virus reverse transcriptase (M-MLV …
Bizarre bacteria defy textbooks by writing new genes - Nature
May 22, 2024 · Now, scientists have discovered an even weirder twist 1. A bacterial version of reverse transcriptase reads RNA as a template to make completely new genes written in DNA.