Neutrophil extracellular traps - Wikipedia
NET activation and release, or NETosis, is a dynamic process that can come in two forms, suicidal and vital NETosis. Overall, many of the key components of the process are similar for both types of …
NETosis (neutrophil extracellular trap) - ScienceDirect
Neutrophil extracellular traps (NETosis) is defined as the process through which active neutrophils release their chromatin contents to form extracellular traps, which aid in the eradication of pathogenic …
What Is Netosis? The Immune System’s Double-Edged Sword
Nov 27, 2025 · Netosis is a distinct form of cellular action performed primarily by neutrophils, the most abundant type of white blood cell and rapid first-responders. Unlike other forms of cell death, Netosis …
NETosis - an overview | ScienceDirect Topics
NETosis is defined as a neutrophil death pathway characterized by the disassembly of the nucleus and the release of chromatin and modified proteins, forming structures called NETs that trap …
NETosis: how vital is it? - American Society of Hematology
Oct 17, 2013 · We summarize how NETs are formed in response to various stimuli and provide evidence that NETosis is not universally a cell death pathway. Here we describe at least 2 different …
Neutrophil extracellular traps in homeostasis and disease
Sep 20, 2024 · Phagocytic receptors like Dectin-1 inhibit NETosis in response to small microorganisms by sequestering NE to phagosomes, while Siglec-5 and Siglec-9 suppress NETosis by limiting …
Molecular mechanisms and therapeutic target of NETosis in diseases
Aug 19, 2022 · This review summarizes the mechanism of NETosis, the receptors associated with NETosis, the pathology of NETosis-induced diseases, and NETosis-targeted therapy.
Neutrophil extracellular traps in immunity and disease - Nature
Oct 9, 2017 · This paper provides evidence for the presence of NETs in the sputum of patients with cystic fibrosis and a role for the protease-dependent mechanism of NETosis in facilitating sputum...
Receptor-Mediated NETosis on Neutrophils - Frontiers
Nov 4, 2021 · In this review, we provide an overview of the immunoreceptor-mediated regulation of NETosis. The pathways involved in the release of NETs during infection or stimulation by …
NETosis: Molecular Mechanisms, Role in Physiology and Pathology
Oct 27, 2020 · In this review, basic mechanisms of NETosis, as well as its role in the pathogenesis of some diseases including COVID-19 are discussed.