Dec 15, 2025 · In this issue of the JCI, Miao et al. demonstrated that MCC tumor survival requires neuroendocrine-lineage transcription factors, which are recruited to superenhancers (SEs) …

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Volume 135, Issue 24December 1, 2025

JCI is a Gold Open Access journal and deposits all published research articles in PubMed Central, which satisfies the NIH Public Access Policy and other similar funding agency …

Dec 15, 2025 · In this issue of the JCI, Miao et al. demonstrated that MCC tumor survival requires neuroendocrine-lineage transcription factors, which are recruited to superenhancers (SEs) …

Nov 15, 2024 · Kurihara C, et al. Crosstalk between nonclassical monocytes and alveolar macrophages mediates transplant ischemia-reperfusion injury through classical monocyte …

Mar 17, 2025 · JCI Insight. 2016;1 (17):e90045. View this article via: JCI Insight CrossRef PubMed Google Scholar Mankia K, et al. EULAR points to consider for conducting clinical …

JCI Insight is a peer-reviewed journal dedicated to biomedical research, ranging from preclinical to clinical studies. JCI Insight is a Gold Open Access journal that has a 2023 Impact Factor of 6.3.

Nguyen et al. report that palmitate triggers ROS-induced Ca2+ overload and mTORC1 activation at the lysosomal membrane, resulting in autophagy defects. Restoring perilysosomal Ca2+ …

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