Comparative analyses have shown that performance varies among rare variant tests, particularly with respect to the underlying phenotype model and the inclusion of noncausal variants. 8, 15 For example ...
Figure 1: HotSpot3D workflow, robustness simulations, and comparison to SpacePAC. Figure 3: Cancer type specificity of intramolecular and intermolecular clusters. Figure 5: Polar plots showing ...
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genomic surveillance has revealed thousands of alterations in structural and non-structural proteins. However, by the end of 2020, viral ...
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Complex engineering of human cell lines reveals genome's unexpected resilience to structural changes
The most complex engineering of human cell lines ever has been achieved by scientists, revealing that our genomes are more resilient to significant structural changes than was previously thought.
Panel A shows the pedigree of the family, with PRLR genotypes identified by bidirectional sequencing. Squares indicate male persons, and circles female persons. The arrow indicates the proband. The ...
Coronavirus disease 2019 (COVID-19) variants have been an ongoing concern since their emergence. The first variant, known as the alpha variant or B1.1.7, was discovered in the UK and quickly became ...
The most complex engineering of human cell lines ever has been achieved by scientists, revealing that our genomes are more resilient to significant structural changes than was previously thought. The ...
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