Various approaches have been developed to identify and quantitate copy-number variation. A new, high-resolution approach that already shows promise is digital PCR. As illustrated by many research ...
SMBE Journals (Molecular Biology and Evolution and Genome Biology and Evolution) Generating genome sequence data from six additional C. psl. strains that differed markedly in the size of their genomes ...
This important study, which tackles the challenge of analyzing genome integrity and instability in unicellular pathogens by introducing a novel single-cell genomics approach, presents compelling ...
Digital PCR (dPCR) is an exceptionally accurate and sensitive method ideally suited for identifying copy number variations (CNVs), also referred to as copy number alterations (CNAs). The Digital ...