Schematic representation of histone-modifying factor recruitment on cccDNA minichromosomes in relation to viral protein HBx. In the presence of HBx, histone-modifying factors such as p300/CBP, Set1A, ...

Paul Martin, MD, FACP, Professor of Medicine and Chief, Division of Hepatology, Center for Liver Disease, University of Miami School of Medicine, Miami, Florida There are no human data correlating ...

Exciting new data from early in vitro and in vivo studies targeting covalently closed circular DNA, which may form the basis of a cure for chronic hepatitis B virus infection. Exciting new data ...

Technique measuring the cccDNA marker may allow earlier detection of hepatocellular carcinoma in patients, reports The Journal of Molecular Diagnostics Philadelphia, April 12, 2018 - Chronic hepatitis ...

Approximately 300 million people worldwide are chronically infected with the hepatitis B virus (HBV) and at high risk of developing liver cirrhosis or hepatocellular carcinoma. Consequently, there is ...

Developing new, more sensitive assays to detect chronic infections, like those from the hepatitis B virus (HBV), is imperative to when trying to manage associated diseases such as cirrhosis and ...

Now that hepatitis C virus has many therapeutic options, biopharma companies have turned their attention to finding a potential cure – or at least a functional cure – for hepatitis B virus (HBV), ...

The study examines the molecular mechanisms governing cccDNA activity and explores potential therapeutic approaches to silence its transcription. By focusing on chromatin-modifying enzymes, viral ...

Chronic hepatitis B virus (HBV) can progress to cirrhosis and hepatocellular carcinoma (HCC). A study describes a new HBV assay that offers advantages over currently used methods because it has the ...

Schematic representation of histone-modifying factor recruitment on cccDNA minichromosomes in relation to viral protein HBx. GA, UNITED STATES, March 24, 2025 /EINPresswire / -- Chronic hepatitis B ...

Chronic hepatitis B virus (HBV) can progress to cirrhosis and hepatocellular carcinoma (HCC). A study published in The Journal of Molecular Diagnostics describes a new HBV assay that offers advantages ...