Cytochrome P450 enzymes constitute a superfamily of haem-containing proteins that catalyse the oxidation of a wide range of exogenous and endogenous compounds. Their function is fundamental to the ...

Enzymes are the molecule factories in biological cells. However, which basic molecular building blocks they use to assemble target molecules is often unknown and difficult to measure. An international ...

Researchers have made a major breakthrough earlier this year in the field of evolutionary conservation of molecular dynamics in enzymes. Their work points to potential applications in health, ...

Using high-speed atomic force microscopy (HS-AFM), the Kanazawa University team led by Mikihiro Shibata filmed the dynamic movements of CaMKII at the single-molecule level. The images revealed that a ...

In this corner: the state-of-the-art enzyme function prediction tool … the Bioinformatic Brawler … the Basic Local Alignment Search Tool for proteins … BLASTp! And in this corner: the contender … the ...

A new artificial intelligence tool can predict the functions of enzymes based on their amino acid sequences, even when the enzymes are unstudied or poorly understood. The researchers said the AI tool, ...

A research team at Leibniz-HKI has described a new enzyme that renders the highly toxic molecule malleicyprol harmless.

Researchers from Tokyo Metropolitan University have developed a new structure determination method using Nuclear Magnetic Resonance (NMR) spectroscopy which shows how different parts of complex ...

Professor Nicolas Doucet and his team at Institut national de la recherche scientifique (INRS) made a major breakthrough earlier this year in the field of evolutionary conservation of molecular ...