Timing of troughs Troughs should be obtained at steady state: approximately prior to the fifth dose IIB Optimal trough concentrations Should be >10 mg/l at a minimum to avoid development of ...

Vancomycin has been associated with nephrotoxicity since first becoming available for clinical use. Until recently, the risk for vancomycin-induced nephrotoxicity was presumed to be minimal -- modern ...

Jennifer Le, PharmD Pediatric patients who attain higher trough levels of the drug may be at higher risk of kidney damage. SAN FRANCISCO—Nephrotoxicity from vancomycin therapy develops more quickly in ...

Successful Migration to a Vancomycin AUC-dosing Protocol: Evaluation, Implementation and Outcomes in an Acute Care Hospital Setting Vancomycin, an antibiotic medication used to treat serious bacterial ...

Results of a small Johns Hopkins Children's Center study show that hospitalized children given high-dose IV infusions of the antibiotic vancomycin to treat drug-resistant bacterial infections face an ...