In a recent study posted to the bioRxiv* preprint server, researchers analyzed the effects of mutations of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) Omicron variant at the atomic ...

Researchers have created the first complete map showing how hundreds of mutations in a key cancer gene affect tumor growth.

Mutations in a single gene, HNF1A, are known to cause MODY3, a rare, early onset form of diabetes. Smaller scale mutations in the very same gene are also common and quietly nudge millions of people ...

Scientists have created a complete map showing how hundreds of possible mutations in a key cancer gene influence tumor growth. The study focused on CTNNB1, a gene that produces the protein β-catenin, ...

Cerebrospinal fluid circulating tumor DNA for the detection and characterization of leptomeningeal metastasis in non-small cell lung cancer. This is an ASCO Meeting Abstract from the 2023 ASCO Annual ...

Experiments from the 1940s established a key tenet of genetics—mutagenesis occurs randomly across the genome. New research, however, suggests that mutations may be less random than originally thought.

In autosomal-dominant AD, mutation type influenced amyloid-PET pegged to estimated years before symptom onset. Some mutations came with more striatal amyloid; some with cortical. CSF Aβ42 did not vary ...