The genetic heritage is not a simple, static list inside the cell nucleus. It unfolds into a dynamic architecture whose ...

DNA's double helix has long stood as the symbol of life’s code. But buried within the genome lies a deeper level of complexity. One of the more intriguing discoveries in recent years is the i-motif—a ...

One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published in Nature.

Researchers have developed a comprehensive atlas that maps DNA methylation—a critical chemical modification governing gene activity—across 39 human cell types, revealing a complex landscape of ...

Scientists depicted the four-dimensional genome model to reveal how DNA folding regulates genes. The discovery helps ...

Scientists map the true nature of the genome with its loops and folds in four dimensions across time and space.

When scientists want to trace how a species has changed over time—and predict its prospects for survival—they turn to DNA. But what if the genetic map guiding them belongs to the wrong animal? Lycium ...

DNA methylation is an epigenetic modification crucial to normal development, with its dysregulation leading to various diseases including cancer. As interest in epigenomics grows, an innovative ...

An international team, including researchers from HSE University, has created the first comprehensive map of quadruplexes—unstable DNA structures involved in gene regulation. For the first time, ...