The type III secretion system (T3SS) is a sophisticated molecular apparatus that many Gram‐negative bacterial pathogens deploy to inject effector proteins directly into host cells. This machinery ...
UMass Amherst biochemists are mapping the molecular structure of a needle-like tool used by bacteria to invade human and mammalian cells to cause such diseases as plague and dysentery. Of particular ...
Six years ago, Michael Niederweis, Ph.D., described the first known toxin of the deadly pathogen Mycobacterium tuberculosis (Mtb), an exotoxin that had gone undetected for 132 years. Now Niederweis ...
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