CRISPR-Cas is used broadly in research and medicine to edit, insert, delete or regulate genes in organisms. TnpB is an ancestor of this well-known 'gene scissor' but is much smaller and thus easier to ...

Scientists have used a gene therapy tool that acts like intelligent molecular scissors to correct the key gene defect in mice with hemophilia B. Scientists have used a gene therapy tool that acts like ...

Researchers from Würzburg, Braunschweig, and the US identifiy Cas12a3 nuclease showing precise activity. Their study is ...

STOCKHOLM — Two scientists have won the Nobel Prize in chemistry for developing a method of genome editing likened to “molecular scissors” that offer the promise of one day curing inherited diseases ...

In Gerold Schank's lab, researchers from the University of Zurich have used protein engineering and an AI model to make the protein TnpB much more effective for genome editing. It was recently ...