The dehydrogenase complexes serve as pivotal regulators in cellular metabolism, orchestrating key oxidative reactions within the tricarboxylic acid (TCA) cycle and beyond. These multi‐enzyme ...
Michihito Kono, Nobuya Yoshida, Kayaho Maeda, Nicole E. Skinner, Wenliang Pan, Vasileios C. Kyttaris, Maria G. Tsokos, George C. Tsokos Proceedings of the National ...
Lung cancer, notorious for its high mortality rates, is a leading cause of cancer-related deaths globally, with metastasis being the primary contributor to poor patient outcomes. A critical factor in ...
While Tinkering With the Beta-Cell... Metabolic Regulatory Mechanisms and New Therapeutic Strategies
The results of the glycerol kinase studies are somewhat surprising in light of good evidence from several laboratories that mitochondrial metabolism of glucose generates important signals for insulin ...
A research group has developed an engineered E. coli strain that converts formic acid and CO2 to pyruvate and produces cellular energy from formic acid through reconstructed one-carbon pathways. The ...
Metabolism, far from being just a housekeeping function, underlies all changes in cell size and function ...
FDA grants a Type A meeting on December 18th to review new and expanded datasets submitted by Saol to help identify a feasible path forward without the need for an additional clinical trial ROSWELL, ...
The Food and Drug Administration (FDA) has accepted for Priority Review the New Drug Application for SL1009 (sodium dichloroacetate oral solution) for the treatment of pyruvate dehydrogenase complex ...
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