Pyruvate dehydrogenase complexes (PDCs) occupy a pivotal role at the interface of glycolysis and the tricarboxylic acid cycle by catalysing the oxidative decarboxylation of pyruvate to acetyl-CoA.
The pyruvate dehydrogenase kinase-3 (PDK3) plays an important role in the regulation of a variety of cancers, including lung, by inhibiting the pyruvate dehydrogenase complex (PDC), shifting energy ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results