Intracellular peptides, generated predominantly via the ubiquitin–proteasome system, have emerged as critical modulators of cell signalling. These peptides play multifaceted roles, ranging from ...

An international research team has succeeded in deciphering a key mechanism that controls the growth of pancreatic cancers.

Cells that are about to die send a signal to an executioner protein, but sometimes, those cells can fight back and regenerate ...

A paper published in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key driver in ...

A new paper published today in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key ...

Precise methods for shredding or repairing and replacing specific cancer-causing proteins in a malignant cell, developed at ...

Maintaining cellular order is a major logistical challenge: Individual mammalian cells contain billions of protein molecules, ...

To stay healthy, our cells rely on a self-cleaning mechanism that removes defective or unnecessary components. This process, ...

A selective protein degradation system known as Golgi membrane-associated degradation (GOMED), which identifies and removes ...

Bacteria in the human gut can directly deliver proteins into human cells, actively shaping immune responses.

A brain protein called ANO2 has emerged as a new piece of the puzzle linking Epstein-Barr virus (EBV) infections and MS ...