Primary immunodeficiency diseases (PIDDs)—now more commonly called inborn errors of immunity (IEI)—are rare genetic disorders that cause at least one part of the immune system to malfunction. Though ...
A firm handshake between proteins on immune cells is important for the body's ability to fight infection. Meanwhile, a weak grip helps explain the poor immune deficiencies caused by a rare genetic ...
Immune system disorders in children can involve an underactive, overactive, or misdirected immune response. Main groups include immunodeficiencies, autoimmune diseases, atopic diseases, and ...
Mortality risk higher among children with primary immunodeficiency diseases infected with SARS-CoV-2
Children with certain immunodeficiency diseases carry mutations in genes that regulate the body's immune system against viral infections and they have a higher mortality rate due to COVID-19. This is ...
Given the heterogeneity and rarity of inborn errors of immunity (IEIs), management guidelines that deal with primary immunodeficiency as a whole are rare. The most recent general guideline, the ...
Please provide your email address to receive an email when new articles are posted on . “In our outpatient clinic, a lot of our primary immunodeficiency (PID) patients complain of fatigue, not being ...
Primary immunodeficiency disorders (PID) can result in chronic and sometimes life-threatening infections. More than 450 PIDs have been described, but timely and accurate diagnoses remain a challenge.
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