The Pre-Initiation Complex (PIC), which consists of Mediator, TFIIA, TFIIB, TFIID, TFIIE, TFIIF, TFIIH, and RNA polymerase II (RNAPII), governs the expression of all protein-coding and most non-coding ...

The influenza virus continues to pose a threat to our health. It triggers seasonal epidemics and, from time to time, potentially serious global pandemics. Existing antiviral drugs are often less ...

Enzymes called RNA polymerases transcribe DNA into RNA. RNA is the intermediary that carries the information contained within DNA to the ribosomes, where the genetic information is synthesized into ...

Researchers studying SARS-CoV-2, the novel coronavirus that causes COVID-19, have published another structure of a viral protein that could be a target for treatments, including Gilead Sciences’s ...

Life's instructions are written in DNA, but it is the enzyme RNA polymerase II (Pol II) that reads the script, transcribing RNA in eukaryotic cells and eventually giving rise to proteins. Scientists ...

New research by German scientists has uncovered another form of coronavirus polymerase. The current polymerase thought to be used for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ...