Researchers at Kumamoto University, Japan have revealed that DNA methylation occurs in the gene that codes serotonin transporter (SERT), a protein that regulates neurotransmitter transmission, in ...

Excitatory neurotransmitters increase the likelihood that a neuron will fire a signal called an action potential in the receiving neuron. There are several types of excitatory neurotransmitters.

Mutations in the gene ANT1 may confer a risk for bipolar disorder through a complex interplay between serotonin and mitochondrial signaling in the brain. These two pathways have been separately ...

Caplyta (lumateperone) was approved for the treatment of schizophrenia in 2019 and for depressive episodes linked to bipolar I or bipolar II disorder (bipolar depression) in 2021. Caplyta can be used ...

Bipolar disorder is a challenging illness with various clinical presentations. In "type one" people struggle with alternating symptoms of full blown mania, and most also have depressive episodes as ...

Though it can be managed, when left untreated, bipolar disorder can completely disrupt a person’s life. This mental health condition causes unusual and sometimes extreme shifts in a person’s mood, ...

A) CpG site where the structure and methylation of the SERT gene were analyzed. Transcription is performed from right to left in the figure, and 5-HTTLPR polymorphism exists in the promoter ...