A recent study posted on the bioRxiv* preprint server explored the glycan shield diversity of sarbecoviruses, furthering the knowledge for developing broad-range pan-coronavirus vaccines. Study: The ...

A type of glycan called “N-glycan” is usually extended by the actions of several enzymes (glycosyltransferases). The terminal sugar “sialic acid” increases protein stability in blood. Once B4GALNT3 ...

In a recent review published in Cellular and Molecular Immunology, researchers discuss the regulatory roles of glycans and glycan-binding proteins (GBPs) in modulating immune responses, particularly ...

Glycans are chains of sugars that attach to cells through proteins or lipids, changing their chemical characteristics. Glycans can be incredibly complex and branched in structure, contributing to the ...

NIST Standard Reference Material (SRM) 3655 helps biopharmaceutical manufacturers perform measurements of glycan molecules in their protein drug products, including the monoclonal antibodies (mAbs) ...

A quiet layer of biology is beginning to change how health is understood, and it sits on the surface of nearly every cell in your body. Scientists now say these tiny sugar structures, once ignored, ...

Specific glycans attached to the GnT-IVa and GnT-IVb can bind to the enzyme’s ligand-binding site, interfering with recognition and binding to the glycosylation proteins’ normal glycoprotein ...