Liver fibrosis is a progressive and potentially reversible condition that results from chronic liver damage, which can be caused by a variety of factors, including metabolic dysfunction-associated ...

Fatty liver disease often leads to chronic liver inflammation and can even result in liver cancer. Scientists from the German Cancer Research Center (DKFZ) and the University of Tübingen have now ...

A new study published in Microbiology Spectrum reports the establishment of a liver-humanized NSG-PiZ mouse model that is fully permissive to hepatitis B virus (HBV) infection. In this model, HBV can ...

Scientists have developed a functional human hepatic tissue in a mouse host. The human hepatic tissue, in the mice, is composed of human hepatocytes and non-parenchymal cells (NPCs) including human ...

Liver infections may not make headlines like the flu or COVID-19, but they quietly impact hundreds of millions of people worldwide. Hepatitis B and C viruses (HBV and HCV) are masters of persistence, ...

Organoids are miniature organs made up of different cell types that exhibit similar structures and functions to real organs. Organoids more closely reflect human physiological and pathological ...