Researchers have found hundreds of metabolic enzymes attached to human DNA inside the cell nucleus. Different tissues and cancers show unique patterns of these enzymes, forming a “nuclear metabolic ...

A research team has conducted a study exploring the role of the mannose pathway in regulating cell fate decisions in low glucose environments. Their work may hold potential for novel therapeutic ...

Preclinical research across multiple cancer types now shows that the NAD+ salvage pathway, the same biological mechanism targeted by popular anti-aging supplements like nicotinamide mononucleotide ...

A research team has conducted a study exploring the role of the mannose pathway in regulating cell fate decisions in low glucose environments. Their work may hold potential for novel therapeutic ...

Scientists have discovered that a rare “mirror-image” version of the amino acid cysteine can dramatically slow the growth of certain cancers while leaving healthy cells largely untouched. Unlike most ...

More than 200 metabolic enzymes, many of which are normally tasked with producing energy in the mitochondria, are also found ...

Cancer cells are often described as “glutamine addicted,” relying heavily on this amino acid to fuel growth. But new research reveals how some tumors sidestep this vulnerability.

Researchers have found evidence of nuclear metabolic enzymes for the first time, contributing to our understanding of cancer ...

A unique property of cancer cells is their ability to undergo metabolic reprogramming, during which they preferentially utilize aerobic glycolysis, glutaminolysis, mitochondrial respiration, and other ...

A recent study published in the journal Frontiers in Endocrinology investigated the role of the short-chain dehydrogenase/reductase 42E member 1 (SDR42E1) enzyme in regulating sterol metabolism and ...