Endosomal trafficking and protein sorting constitute fundamental processes that govern the intracellular localisation and recycling of membrane proteins in eukaryotic cells. Endosomes act as central ...

Located at the cellular interface, membrane proteins play critical regulatory roles in the signaling between a cell and its interacting environment, making them popular and ideal drug targets.

Cellular membrane proteins play many important roles throughout the body, including transporting substances in and out of the cell, transmitting signals, speeding up reactions and helping neighboring ...

The ER-phagy receptor FAM134B is initially distributed via the membrane surface (left). Its IDRs move back and forth in a largely disordered manner, like tentacles. The formation of local clusters ...

Membrane proteins are essential for fundamental biological processes, and are important for drug discovery, understanding disease mechanisms, and advancing structural biology. Their intricate roles in ...

Cellular membrane proteins play important roles in cellular transport, signaling, and cell-to-cell communication. Malfunction in membrane proteins can lead to serious diseases, such as cancer. However ...

F.-U. Hartl, W. Neupert, "Protein sorting to mitochondria: evolutionary conservations of folding and assembly," Science, 247:930-38, 1990. Franz-Ulrich Hartl (University of Munich, Germany): "In this ...

Nuclera, the biotechnology company accelerating protein expression and optimization through its benchtop eProtein Discovery™ system, today announced the addition of a new membrane protein workflow to ...

Scientists have long known that cellular membranes vary in thickness, but measuring those differences inside actual cells has ...

Cellular membrane proteins play many important roles throughout the body, including transporting substances in and out of the cell, transmitting signals, speeding up reactions and helping neighboring ...