Tandem mass spectrometry is a powerful tool in proteomics. By ionizing peptides and then fragmenting those ions into smaller product ions, researchers can determine the biomolecules’ amino acid ...

Mass spectrometry has emerged as an indispensable tool for the structural elucidation of oligosaccharides, offering unrivalled sensitivity and precision in the analysis of complex carbohydrate ...

Effective protein characterization depends on the precise isolation and fragmentation of peptide ions within the mass spectrometer, typically coupled with liquid chromatography (LC-MS/MS). In a ...

Sensitivity is a fundamental performance characteristic of a mass spectrometer. Increasingly higher sensitivities are in constant demand in order to characterize and quantify analytes that are at an ...

Electron ionization (EI) is a hard ionization method that is typically used with gas chromatography-mass spectrometry (GC-MS). The mass spectral fragmentation patterns generated by EI are used for ...

The overall strategy of bottom-up proteomics involves four main stages: sample preparation, protein digestion, peptide analysis via liquid chromatography (LC) separation, and mass spectrometry (MS) ...

In Star Trek, Mr. Spock’s hand-held tricorder can instantly tell what something is made of. We don’t have tricorders yet, but we’re getting close. Portable devices just a little too big to hold in one ...