Researchers at Oregon Health & Science University (OHSU) report that MYC, a protein that is overactive in most human cancers, ...

When Laura Soucek first used Omomyc to block MYC signalling in mice, she spent most of the night in the lab. “People thought that these mice would liquefy,” recalls Soucek, then a postdoc at the ...

Pancreatic cancer is one of the deadliest cancers worldwide, with a five-year survival rate of 13%. The poor prognosis is due in part both to late detection and the cancer’s capacity to adapt and ...

The cancer gene MYC camouflages tumors by suppressing alarm signals that normally activate the immune system. This finding from a new study offers a promising way to improve existing cancer therapies ...

Northwestern Medicine investigators have discovered a new combination approach that may improve the efficacy of MYC inhibitor drugs for treating aggressive and treatment-resistant cancers, according ...

Novel Treatment Targets in Sarcoma: More Than Just the GIST MYC has proven to be a highly potent oncoprotein when it is overexpressed, but is also a pleiotropic transcription factor essential for ...

PHILADELPHIA--The cancer gene MYC is among the most commonly overexpressed oncogenes in human cancers. Most human cancers demonstrate high levels of MYC or its biological partners, including those of ...

MYC family genes are essential for the human organism. According to current knowledge, they regulate the expression of most cellular genes. Misregulation of MYC proteins significantly contributes to ...

Gastric cancer is one of the most common malignant cancers worldwide. Since the stage of early gastric cancer usually lasts for a long time and lacks obvious symptoms, the diagnosis of early gastric ...

The landmark success of a drug against an ‘undruggable’ cancer is spurring fresh optimism in the quest to treat seemingly ...

A protein best known for driving cancer growth also helps damaged tumor cells survive by repairing their DNA, according to a new study that could influence how some cancers are treated. Researchers at ...