In a recent study, Stevens researchers have shown how colorectal cancers can evolve from mature intestinal cells that revert to stem cells. These findings explain why colorectal cancers are so ...

A detailed cellular study of Crohn's disease has mapped how gene activity changes across more than 50 cell types in the gut.

Enterobactin, a molecule produced by gut bacteria, may hold a surprising key to reducing intestinal inflammation. Not by ...

Human organoids are 3D cell cultures derived from adult stem cells and maintain the variable distribution of epithelial cells seen in primary tissue. They can recapitulate the mechanisms of epithelial ...

A signaling system known as the Wnt pathway plays a central role in how cells in the intestine grow, divide and renew ...

Researchers have solved a cellular mystery that may lead to better therapies for colorectal and other types of cancer. A professor of pediatrics-developmental biology and an assistant professor of ...

Researchers at the Francis Crick Institute have shown that the Cryptosporidium parasite exports a protein into infected intestinal cells, altering the gut environment and enabling the parasite to ...

A new study reported in Nature has determined that the amino acid cysteine could promote regeneration among cells in the small intestine. The work showed that cysteine can activate an immune signaling ...

Researchers found that a small population of immune cells in the mouse intestine prevents allergic responses to food, suggesting that targeting such cells therapeutically could potentially lead to a ...

The human small intestine is an essential organ that helps us absorb nutrients and vitamins from food. It is an average of 6 meters long and is covered with millions of villi that are separated by ...

Every 24 hours, the human body manufactures and discards roughly 330 billion cells, a turnover rate that amounts to about one ...