Researchers at the Center for Genomic Regulation (CRG) in Barcelona have created the first blueprint of the human spliceosome, the most complex and intricate molecular machine inside every cell. The ...

Researchers have created the first blueprint of the human spliceosome, the most complex and intricate molecular machine in human biology. The vast majority of human genes -- more than nine in ten -- ...

AlphaGenome is a leap forward in the ability to study the human blueprint. But the fine workings of our DNA are still largely ...

A new research paper featured as the cover of Volume 17, Issue 12 of Aging-US was published on December 22, 2025, titled “A combination of differential expression and network connectivity analyses ...

Discover the innovative TECHNO platform for full-length gene humanisation, enhancing models for human gene function.

In an important new study, Chinese researchers have discovered the previously unrecognized role of alternative splicing of ...

Humanized mouse models are essential for investigating human gene function; however, the complete replacement of mouse genes ...

Frontotemporal dementia (FTD) often strikes our most human traits, such as the ability to speak and to interact on social and emotional levels. Now, research led by Lorenzo Pasquini and William Seeley ...

A human-specific NOVA1 variant changed mouse vocalizations, potentially providing insights into the evolution of language. Darnell said the switch to the new NOVA1 variant likely occurred between ...