How major nuclear protein complexes control specialized gene regulation in cancer and beyond

Precision and timing of gene expression is essential for normal biological functions and, when disrupted, can lead to many ...
Nanowerk

Gene: The Fundamental Unit of Heredity

A gene is a fundamental unit of heredity, consisting of a specific sequence of DNA that encodes the instructions for making a particular protein or set of proteins. Genes are passed down from parents ...
eLife

A differentiable model for optimizing the genetic drivers of synaptogenesis

This study presents SynaptoGen, a differentiable extension of connectome models that links gene expression, protein-protein interaction probabilities, synaptic multiplicity, and synaptic weights, and ...