Bcl2-associated athanogene-1 protein (Bag1) acts as a co-chaperone of heat shock protein 70 and heat shock cognate 70 and regulates multiple cellular processes, including cell proliferation, apoptosis ...

Image Caption: The human and mouse expression profile of FGF8. (A) Relative abundance of FGF8 in adult human tissues from the Genotype-Tissue Expression (GTEx V8) Project Consortium (TPM, transcripts ...

The Human Cell Atlas project has delivered a fresh tranche of data mapping fibroblasts in healthy and diseased skin and pointing to drug targets with potential in multiple diseases across a range of ...

Mestag Therapeutics has been working to change how fibroblasts are activated and how they expand. Now, Merck & Co. wants in—penning a $1.9 billion biobucks deal to collaborate on new therapies for ...

After 10 years, members of the 4D Nucleome consortium have successfully completed the first phase of a project that aims to map the 3D organization of the human genome and how it changes over time, ...

Human fibroblasts comprise diverse populations with specialized roles in tissue homeostasis and pathology that are controlled by developmental and environmental signals. Fibroblasts are specialised ...