Structural and mechanistic insight into Holliday-junction dissolution by Topoisomerase IIIα and RMI1
Repair of DNA double-strand breaks via homologous recombination can produce double Holliday junctions (dHJs) that require enzymatic separation. Topoisomerase IIIα (TopIIIα) together with RMI1 ...
Testing the dissolution rates of a pharmaceutical formulation (also known as in vitro availability) aids drug quality control and is a compulsory requirement of the British, European and US ...
To achieve reliable and reproducible results, it is important that analysts understand the importance of correctly setting up and sampling from the chosen apparatus. In addition to use of dissolution ...
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Understanding Particle Drift and its Influence on Oral Drug Absorption Using Flux Tools
In this interview, Karl Box from Pion outlines the benefits of particle drift analysis using flux tools and how this can be used to enhance oral drug absorption in pharmaceutical research. Pion's ...
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