To many working biologists, DNA-modifying enzymes are tools, not unlike a pair of molecule-sized scissors. To Dr. Barry Stoddard, a professor in the Basic Sciences division at Fred Hutch, these ...

Enzymes that cut DNA at specific sites are called endonucleases; these enzymes play many roles in genomic replication, fidelity, and defense. The initial discovery of restriction endonucleases in the ...

There are many health problems that can be traced back to errors in the genetic code. There are also many potential benefits to genetic engineering outside of healthcare. Nature has already found ways ...

Genetic information encoded in genomic DNA is transcribed to mRNAs and then the codons on mRNA are decoded by transfer RNAs (tRNAs) during protein synthesis. tRNAs deliver amino acids to ribosomes and ...

In crisis, the nucleus calls antioxidant enzymes to the rescue. The nucleus being metabolically active is a profound paradigm shift with implications for cancer research. In crisis, the nucleus calls ...

A few years ago, the advent of technology known as CRISPR was a major breakthrough in the scientific world. Developed from a derivative of the immune system of bacteria, CRISPR enables double strands ...