EurekAlert!

Overexpressed Cyclin D1 and CDK4 proteins are responsible for the resistance to CDK4/6 inhibitor in breast cancer that can be reversed by PI3K/mTOR Inhibitors

This study is carried out by Prof. Qiang Liu (Breast Tumor Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University). In this study, researchers found that the palbociclib-resistant breast cancer ...
ascopubs.org

Expression of cyclin D1 and its relation with ER, PgR, C-erbB2, Ki-67, and p53 in breast cancer.

Incidental lymphoma during sentinel lymph node biopsy for breast cancer. Background: To evaluate the cyclin D1 expression in breast cancer patients and to investigate its correlation with other ...
Nature

Inhibition of cell cycle progression by dual phosphatidylinositol-3-kinase and mTOR blockade in cyclin D2 positive multiple myeloma bearing IgH translocations

Multiple myeloma (MM) is the second most common haematopoietic cancer and is caused by an accumulation of malignant plasma cells in the bone marrow. Although the recent use of proteasome inhibitors ...
Cure Today

Closer to a Cure for Mantle Cell Lymphoma

Mantle Cell Lymphoma (MCL), as described in this issue of CURE®, has an interesting and inspiring story. It was one of the first cancers known to have a genetic abnormality-chromosomal translocation t ...