Tuojie Biotech (Shanghai) Co. Ltd. has prepared oxygen-containing fused tricyclic derivatives acting as CDK2/cyclin E1 and/or CDK4/cyclin D1 inhibitors. As such, they are reported to be potentially ...

Worldwide, more than a million breast cancer patients have been treated with cyclin-dependent kinase 4/6 (CDK4/6) inhibitors, ...

Blood TCTP as a biomarker associated with immunosuppressive features and resistance to immunotherapy in metastatic gastric cancer. This is an ASCO Meeting Abstract from the 2025 ASCO Gastrointestinal ...

A new review highlights growing evidence that cyclin-dependent kinase (CDK) inhibitors—already used in over a million breast cancer patients—could benefit other cancers through novel drug combinations ...