In the last five years, neuronal pentraxins have emerged as potential markers of synaptic loss. In the case of NPTX2, researchers may now be able to explain why. In the March 29 Science Translational ...

Synaptic pruning is a crucial neurodevelopmental process through which the brain refines its neural circuitry by systematically eliminating excess or weak synaptic connections. During early childhood ...

Synaptic pruning is the process in which the brain removes neurons and synapses that it does not need. This usually takes place when a person is 2–10 years old. The brain contains millions of neurons ...

Researchers led by a group at the Institute of Brain Science, Nagoya City University Graduate School of Medical Sciences and the Nagoya City University School of Medicine report that they have shed ...

A multidisciplinary team of scientists has discovered the mechanism that controls synaptic pruning of new neurons in the adult brain. The team discovered that microglial cells control the number of ...

A research group led by Kazunobu Sawamoto, a professor at Institute of Brain Science, Nagoya City University Graduate School of Medical Sciences and National Institute for Physiological Sciences, and ...

Synaptic pruning is a little like sleep. We know both processes are important to healthy brain function, but we don't know exactly how they happen, nor how to reliably treat problems in the system.