Case-cohort study designs represent a cost-effective and efficient strategy for analysing time-to-event data, particularly when the event of interest is rare. By selecting a random subcohort along ...

Different approaches to cohort study design in the context of biomarkers of aging. Biomarkers of aging are commonly validated using cross-sectional or longitudinal study designs. Cross-sectional ...

Improved Cancer-Specific Risk Stratification by the Lymph Node Ratio-Based Nomogram: A Potential Role in Guiding Postoperative Management Decisions for Oral Cavity Carcinoma We propose a novel ...

Case-cohort study design has been widely used for its cost-effectiveness. In any real study, there are always other important outcomes of interest beside the failure time that the original case-cohort ...

Introduction Students enrolling in higher education often adopt lifestyles linked to worse mental health, potentially contributing to the peak age onset of mental health problems in early adulthood.

Objectives We explored whether a spike in running distance during a single session or over 1 week, compared with the preceding period, was associated with increased risk of running-related overuse ...

Background Exercise stress echocardiography (ESE) is widely used to detect inducible myocardial ischaemia. However, a substantial proportion of ESEs remains inconclusive or shows abnormal ...