FDA's requirements for the use of dofetilide are described, and one hospital's strategy for meeting the requirements is discussed. Dofetilide is a specific class III antiarrhythmic agent approved for ...

Atrial fibrillation (AF) is a growing clinical problem associated with increased morbidity and mortality Currently available antiarrhythmic drugs (AADs) can be highly effective in acute cardioversion ...

Sotalol HCl 15mg/mL; soln for IV infusion after dilution. Sotalol has both beta-adrenoreceptor blocking (Vaughan Williams Class II) and cardiac action potential duration prolongation (Vaughan Williams ...

Two phase 3 trials of dronedarone, a novel class III antiarrhythmic agent currently in development worldwide, have demonstrated that the drug is safe and effective for the maintenance of normal sinus ...

Dofetilide is a class III antiarrhythmic drug that is used for maintenance of sinus rhythm in patients with atrial fibrillation. Dofetilide blocks potassium channels in phase 3 of the action potential ...