Over the past few decades, advances in hematology have illuminated how a delicate balance between stem cell self-renewal and differentiation sustains healthy blood formation. In myelodysplastic ...

SEATTLE--(BUSINESS WIRE)--Parse Biosciences, the leader in accessible and scalable single cell sequencing, today affirmed their plans to proceed with development and future release of their Evercode™ ...

Genome-wide chromatin accessibility profiling reveals how myelodysplastic syndrome (MDS) stem cells progressively lose normal stem-cell features and acquire myeloid progenitor-like characteristics.

Single-cell analyses have emerged as powerful tools for studying cellular heterogeneity and gene regulation. Single-cell chromatin accessibility sequencing (scCAS) is a key technology that enables the ...

This is a preview. Log in through your library . Abstract Allopolyploidization, resulting in divergent genomes in the same cell, is believed to trigger a “genome shock”, leading to broad genetic and ...

Determining where transcription factors (TFs) bind in genomes provides insight into which transcriptional programs are active across organs, tissue types, and environmental conditions. Recent advances ...

Researchers showed that chronic colitis leaves a long-lasting epigenetic memory in colonic stem cells, persisting for more than 100 days after recovery in mice. This memory is marked by durable ...