Fabhalta slowed eGFR decline by 48% vs placebo over two years, demonstrating kidney function preservation1 Clinically meaningful improvements of protein in urine observed as early as two weeks, with s ...

Mannose-binding lectin (MBL) is a soluble C-type lectin that recognises carbohydrate patterns on a wide range of pathogens and initiates the lectin pathway of complement activation. Upon binding to ...

The treatment landscape for C3G has historically depended on the off-label use of multiple prescription therapies, ...

The complement system, a central component of innate immunity, exerts a dual influence on cerebral ischaemia, driving both acute tissue injury and later reparative processes. Following arterial ...